Bis benzothiophene Schiff bases: synthesis and in silico-guided biological activity studies
نویسندگان
چکیده
منابع مشابه
synthesis and characterization of some macrocyclic schiff bases
ماکروسیکلهای شیف باز از اهمیت زیادی در شیمی آلی و دارویی برخوردار می باشند. این ماکروسیکلها با دارابودن گروه های مناسب در مکانهای مناسب می توانند فلزاتی مثل مس، نیکل و ... را در حفره های خود به دام انداخته، کمپلکسهای پایدار تولید نمایند. در این پایان نامه ابتدا یک دی آلدئید آروماتیک از گلیسیرین تهیه می شود و در مرحله بعدی واکنش با دی آمینهای آروماتیک و یا آلیفاتیک در رقتهای بسیار زیاد منجر به ت...
15 صفحه اولSynthesis and Biological Evaluation of Schiff Bases
Cinchophen (I) was synthesized from pyruvic acid, aniline and benzaldehyde by Doebner synthesis. Cinchophen acid chloride (II) was synthesised from cinchophen and oxalyl chloride by acylation reaction. The 2phenylquinoline-4-carboxylic acid amide (III) was synthesized from acid chloride and ammonia by simple reaction. The 2-phenylquinoline-4-carboxylic acid amine (IV) was synthesized from cinch...
متن کاملSynthesis of biologically active novel bis Schiff bases, bis hydrazone and bis guanidine derivatives
A number of bis Schiff′s bases 3a-d have been synthesized by condensation of 2,4,8,10 tetraoxaspiro[5,5]undecane 3,9dipropanamine 1 with furfural, indole-3-aldehyde, 2-acetylpyridine, 4-acetylpyridine and 5a-c by condensation of 1,4-bis (3-aminopropyl) piperazine 4 with indole-3-aldehyde, 2-acetylpyridine, 4-acetylpyridine, in high yields by using microwave irradiation. Bis hydrazone derivative...
متن کاملSynthesis, Characterization and Biological Evaluation of Schiff Bases of Propanedihydrazide
A Schiff base series of malonohydrazide was synthesized by reaction of malonohydrazide with various aldehydes. Hydrazine hydrate was reacted with ethyl malonate in ethanol to give malonohydrazide in very good yields. The synthesized compounds were characterized using FTIR and NMR spectroscopies. The biological evaluation of the Schiff bases was carried against Gram +tive and Gram –tive bacteria...
متن کاملSynthesis, Structural, and Biological Studies of Some Schiff Bases and Their Metal Complexes
New bidentate or tridentate Schiff bases and their VO(II) and Co(II) complexes formed by the condensation of methyl isobutyl ketone with nicotinamide (mna)/2-amino-4-chlorophenol (map) and 2-hydroxy acetophenone with nicotinamide (han)/isoniazide (hai). Physicochemical characterization has been carried out to determine the structure of the complexes. The FAB mass and thermal data show degradati...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: TURKISH JOURNAL OF CHEMISTRY
سال: 2020
ISSN: 1303-6130
DOI: 10.3906/kim-2004-78